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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLL2
All Species:
13.64
Human Site:
T1699
Identified Species:
50
UniProt:
O14686
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14686
NP_003473.3
5262
564185
T1699
G
E
P
D
S
P
W
T
G
S
G
G
T
T
P
Chimpanzee
Pan troglodytes
XP_519508
4802
529408
Q1696
E
Q
E
W
K
F
R
Q
Q
M
R
Q
K
S
K
Rhesus Macaque
Macaca mulatta
XP_001099471
5209
557834
T1646
G
E
P
D
S
P
W
T
G
S
G
G
T
T
P
Dog
Lupus familis
XP_543684
5287
566794
T1691
G
E
P
D
S
P
W
T
G
S
G
G
T
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH4
4903
540168
I1596
K
S
P
A
F
N
A
I
A
S
D
P
N
S
S
Rat
Rattus norvegicus
XP_002729900
5543
595507
T1931
G
E
P
D
S
P
W
T
G
S
G
G
T
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRW8
2431
259810
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.3
95.3
93.4
N.A.
27.8
85
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
Protein Similarity:
100
43.2
96
95.1
N.A.
41.7
87.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
20
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
15
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
58
0
0
0
0
0
0
15
0
0
0
0
% D
% Glu:
15
58
15
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
15
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
58
0
0
0
0
0
0
0
58
0
58
58
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% I
% Lys:
15
0
0
0
15
0
0
0
0
0
0
0
15
0
15
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
72
0
0
58
0
0
0
0
0
15
0
0
58
% P
% Gln:
0
15
0
0
0
0
0
15
15
0
0
15
0
0
0
% Q
% Arg:
0
0
0
0
0
0
15
0
0
0
15
0
0
0
0
% R
% Ser:
0
15
0
0
58
0
0
0
0
72
0
0
0
29
15
% S
% Thr:
0
0
0
0
0
0
0
58
0
0
0
0
58
58
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
15
0
0
58
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _